Endocrine Abstracts

Objective: Human immunodeficiency virus (HIV)-infected patients demonstrate an increased risk of osteoporosis and fractures. The pathophysiology of HIV-induced bone loss is complex and remains largely unknown. Recent studies have identified a molecular signature of small non-coding RNAs (microRNAS) in patients with osteoporosis, but data are lacking in HIV-infected patients. The aim of the present study was to investigate the expression profile of microRNAs related to bone met...

Background: Primary hyperparathyroidism (PHPT) has been linked to glucose homeostasis disorders, leading to insulin resistance and type 2 diabetes mellitus. Previous small studies evaluating the effect of parathyroidectomy (PTX) on various parameters of glucose metabolism have produced conflicting results. The impact of PTX on incretin hormone levels has not been studied yet. The aim of this pilot study was to investigate the effect of PTX on markers of glucose metabolism and ...